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Hep88 mAb-initiated paraptosis-like PCD pathway in hepatocellular carcinoma cell line through the binding of mortalin (HSPA9) and alpha-enolase

BACKGROUND: Hepatocellular carcinoma (HCC) is the most prevalent hepatic cancer worldwide. Currently, a targeted therapy via monoclonal antibodies (mAbs) specific to tumor-associated antigen is undergoing continual development in HCC treatment. METHODS: In this regard, after establishing and consequ...

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Detalles Bibliográficos
Autores principales: Rojpibulstit, Panadda, Kittisenachai, Suthathip, Puthong, Songchan, Manochantr, Sirikul, Gamnarai, Pornpen, Jitrapakdee, Sarawut, Roytrakul, Sittiruk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364037/
https://www.ncbi.nlm.nih.gov/pubmed/25788858
http://dx.doi.org/10.1186/s12935-014-0069-9