Analysis of the functional repertoire of a mutant form of survivin, K129E, which has been linked to lung cancer

BACKGROUND: Survivin is a protein that is normally present only in G2 and M-phases in somatic cells, however, in cancer cells, it is expressed throughout the cell cycle. A prosurvival factor, survivin is both an inhibitor of apoptosis and an essential mitotic protein, thus it has attracted much atte...

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Detalles Bibliográficos
Autores principales: Aljaberi, Aysha M, Webster, Jamie RM, Wheatley, Sally P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364043/
https://www.ncbi.nlm.nih.gov/pubmed/25788861
http://dx.doi.org/10.1186/s12935-014-0078-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364043/
https://www.ncbi.nlm.nih.gov/pubmed/25788861
http://dx.doi.org/10.1186/s12935-014-0078-8

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