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Analysis of the functional repertoire of a mutant form of survivin, K129E, which has been linked to lung cancer
BACKGROUND: Survivin is a protein that is normally present only in G2 and M-phases in somatic cells, however, in cancer cells, it is expressed throughout the cell cycle. A prosurvival factor, survivin is both an inhibitor of apoptosis and an essential mitotic protein, thus it has attracted much atte...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364043/ https://www.ncbi.nlm.nih.gov/pubmed/25788861 http://dx.doi.org/10.1186/s12935-014-0078-8 |