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A Novel Mouse Model for Stable Engraftment of a Human Immune System and Human Hepatocytes

Hepatic infections by hepatitis B virus (HBV), hepatitis C virus (HCV) and Plasmodium parasites leading to acute or chronic diseases constitute a global health challenge. The species tropism of these hepatotropic pathogens is restricted to chimpanzees and humans, thus model systems to study their pa...

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Detalles Bibliográficos
Autores principales: Strick-Marchand, Helene, Dusséaux, Mathilde, Darche, Sylvie, Huntington, Nicholas D., Legrand, Nicolas, Masse-Ranson, Guillemette, Corcuff, Erwan, Ahodantin, James, Weijer, Kees, Spits, Hergen, Kremsdorf, Dina, Di Santo, James P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364106/
https://www.ncbi.nlm.nih.gov/pubmed/25782010
http://dx.doi.org/10.1371/journal.pone.0119820