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Using optical mapping data for the improvement of vertebrate genome assemblies

Optical mapping is a technology that gathers long-range information on genome sequences similar to ordered restriction digest maps. Because it is not subject to cloning, amplification, hybridisation or sequencing bias, it is ideally suited to the improvement of fragmented genome assemblies that can...

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Detalles Bibliográficos
Autores principales: Howe, Kerstin, Wood, Jonathan MD
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364110/
https://www.ncbi.nlm.nih.gov/pubmed/25789164
http://dx.doi.org/10.1186/s13742-015-0052-y