Cargando…

Preparation of poly(β-L-malic acid)-based charge-conversional nanoconjugates for tumor-specific uptake and cellular delivery

In this study, a multifunctional poly(β-L-malic acid)-based nanoconjugate with a pH-dependent charge conversional characteristic was developed for tumor-specific drug delivery. The short branched polyethylenimine-modified poly(β-L-malic acid) (PEPM) was first synthesized. Then, the fragment HAb18 F(...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhou, Qing, Yang, Tiehong, Qiao, Youbei, Guo, Songyan, Zhu, Lin, Wu, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364157/
https://www.ncbi.nlm.nih.gov/pubmed/25792828
http://dx.doi.org/10.2147/IJN.S78547