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Preparation of poly(β-L-malic acid)-based charge-conversional nanoconjugates for tumor-specific uptake and cellular delivery
In this study, a multifunctional poly(β-L-malic acid)-based nanoconjugate with a pH-dependent charge conversional characteristic was developed for tumor-specific drug delivery. The short branched polyethylenimine-modified poly(β-L-malic acid) (PEPM) was first synthesized. Then, the fragment HAb18 F(...
Autores principales: | Zhou, Qing, Yang, Tiehong, Qiao, Youbei, Guo, Songyan, Zhu, Lin, Wu, Hong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364157/ https://www.ncbi.nlm.nih.gov/pubmed/25792828 http://dx.doi.org/10.2147/IJN.S78547 |
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