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Differential modulation of repetitive firing and synchronous network activity in neocortical interneurons by inhibition of A-type K(+) channels and I(h)

GABAergic interneurons provide the main source of inhibition in the neocortex and are important in regulating neocortical network activity. In the presence 4-aminopyridine (4-AP), CNQX, and D-APV, large amplitude GABA(A)-receptor mediated depolarizing responses were observed in the neocortex. GABAer...

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Detalles Bibliográficos
Autores principales: Williams, Sidney B., Hablitz, John J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364302/
https://www.ncbi.nlm.nih.gov/pubmed/25852481
http://dx.doi.org/10.3389/fncel.2015.00089