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NBD delivery improves the disease phenotype of the golden retriever model of Duchenne muscular dystrophy
BACKGROUND: Duchenne muscular dystrophy (DMD) is caused by mutations in the dystrophin gene and afflicts skeletal and cardiac muscles. Previous studies showed that DMD is associated with constitutive activation of NF-κB, and in dystrophin-deficient mdx and utrophin/dystrophin (utrn(-/-);mdx) double...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364341/ https://www.ncbi.nlm.nih.gov/pubmed/25789154 http://dx.doi.org/10.1186/2044-5040-4-18 |