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NBD delivery improves the disease phenotype of the golden retriever model of Duchenne muscular dystrophy

BACKGROUND: Duchenne muscular dystrophy (DMD) is caused by mutations in the dystrophin gene and afflicts skeletal and cardiac muscles. Previous studies showed that DMD is associated with constitutive activation of NF-κB, and in dystrophin-deficient mdx and utrophin/dystrophin (utrn(-/-);mdx) double...

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Detalles Bibliográficos
Autores principales: Kornegay, Joe N, Peterson, Jennifer M, Bogan, Daniel J, Kline, William, Bogan, Janet R, Dow, Jennifer L, Fan, Zheng, Wang, Jiahui, Ahn, Mihye, Zhu, Hongtu, Styner, Martin, Guttridge, Denis C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364341/
https://www.ncbi.nlm.nih.gov/pubmed/25789154
http://dx.doi.org/10.1186/2044-5040-4-18