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Tfap2a Promotes Specification and Maturation of Neurons in the Inner Ear through Modulation of Bmp, Fgf and Notch Signaling

Neurons of the statoacoustic ganglion (SAG) transmit auditory and vestibular information from the inner ear to the hindbrain. SAG neuroblasts originate in the floor of the otic vesicle. New neuroblasts soon delaminate and migrate towards the hindbrain while continuing to proliferate, a phase known a...

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Detalles Bibliográficos
Autores principales: Kantarci, Husniye, Edlund, Renee K., Groves, Andrew K., Riley, Bruce B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364372/
https://www.ncbi.nlm.nih.gov/pubmed/25781991
http://dx.doi.org/10.1371/journal.pgen.1005037