Utilizing Targeted Mass Spectrometry to Demonstrate Asf1-Dependent Increases in Residue Specificity for Rtt109-Vps75 Mediated Histone Acetylation

In Saccharomyces cerevisiae, Rtt109, a lysine acetyltransferase (KAT), associates with a histone chaperone, either Vps75 or Asf1. It has been proposed that these chaperones alter the selectivity of Rtt109 or which residues it preferentially acetylates. In the present study, we utilized a label-free...

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Detalles Bibliográficos
Autores principales: Kuo, Yin-Ming, Henry, Ryan A., Huang, Liangqun, Chen, Xu, Stargell, Laurie A., Andrews, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364511/
https://www.ncbi.nlm.nih.gov/pubmed/25781956
http://dx.doi.org/10.1371/journal.pone.0118516

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364511/
https://www.ncbi.nlm.nih.gov/pubmed/25781956
http://dx.doi.org/10.1371/journal.pone.0118516

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