Structural and Enzymatic Characterization of the Choline Kinase LicA from Streptococcus pneumoniae

LicA plays a key role in the cell-wall phosphorylcholine biosynthesis of Streptococcus pneumonia. Here we determined the crystal structures of apo-form LicA at 1.94 Å and two complex forms LicA-choline and LicA-AMP-MES, at 2.01 and 1.45 Å resolution, respectively. The overall structure adopts a cano...

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Detalles Bibliográficos
Autores principales: Wang, Lei, Jiang, Yong-Liang, Zhang, Jing-Ren, Zhou, Cong-Zhao, Chen, Yuxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364537/
https://www.ncbi.nlm.nih.gov/pubmed/25781969
http://dx.doi.org/10.1371/journal.pone.0120467

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364537/
https://www.ncbi.nlm.nih.gov/pubmed/25781969
http://dx.doi.org/10.1371/journal.pone.0120467

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