Root of Polygonum cuspidatum extract reduces progression of diabetes-induced mesangial cell dysfunction via inhibition of platelet-derived growth factor-BB (PDGF-BB) and interaction with its receptor in streptozotocin-induced diabetic rats

BACKGROUND: Platelet-derived growth factor–BB (PDGF-BB) is highly expressed in the renal tissues of patients with diabetic nephropathy, and it plays an important role in the initiation and progression of diabetic nephropathy. The aim of this study was to evaluate the protective effects of root of Po...

Descripción completa

Detalles Bibliográficos
Autores principales: Sohn, Eunjin, Kim, Junghyun, Kim, Chan-Sik, Jo, Kyuhyung, Lee, Yun Mi, Kim, Jin Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364577/
https://www.ncbi.nlm.nih.gov/pubmed/25495844
http://dx.doi.org/10.1186/1472-6882-14-477

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364577/
https://www.ncbi.nlm.nih.gov/pubmed/25495844
http://dx.doi.org/10.1186/1472-6882-14-477

Ejemplares similares