Endogenous antibodies contribute to macrophage-mediated demyelination in a mouse model for CMT1B

BACKGROUND: We could previously identify components of both the innate and the adaptive immune system as disease modifiers in the pathogenesis of models for Charcot-Marie-Tooth (CMT) neuropathies type 1B and 1X. As part of the adaptive immune system, here we investigated the role of antibodies in a...

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Detalles Bibliográficos
Autores principales: Klein, Dennis, Groh, Janos, Weishaupt, Andreas, Martini, Rudolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364634/
https://www.ncbi.nlm.nih.gov/pubmed/25879857
http://dx.doi.org/10.1186/s12974-015-0267-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364634/
https://www.ncbi.nlm.nih.gov/pubmed/25879857
http://dx.doi.org/10.1186/s12974-015-0267-y

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