Influence of quinacrine and chloroquine on the in vitro 3′-azido-3′-deoxythymidine antiretroviral effect

BACKGROUND: Antimalarials quinacrine (Qc) and chloroquine (Cq) intercalate DNA, potentiate the activity of other drugs and have lysosomotropic, anti-inflammatory and antiviral activities that could increase the effect of the 3′-azido-3′-deoxythymidine (AZT) antiretroviral agent. The aim of the curre...

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Detalles Bibliográficos
Autores principales: Torres, Klintsy J, Reyes-Terán, Gustavo, Sotelo, Julio, Jung-Cook, Helgi, Aguirre-Cruz, Lucinda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364635/
https://www.ncbi.nlm.nih.gov/pubmed/25788967
http://dx.doi.org/10.1186/s12981-015-0048-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364635/
https://www.ncbi.nlm.nih.gov/pubmed/25788967
http://dx.doi.org/10.1186/s12981-015-0048-9

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