Cargando…

Influence of quinacrine and chloroquine on the in vitro 3′-azido-3′-deoxythymidine antiretroviral effect

BACKGROUND: Antimalarials quinacrine (Qc) and chloroquine (Cq) intercalate DNA, potentiate the activity of other drugs and have lysosomotropic, anti-inflammatory and antiviral activities that could increase the effect of the 3′-azido-3′-deoxythymidine (AZT) antiretroviral agent. The aim of the curre...

Descripción completa

Detalles Bibliográficos
Autores principales:	Torres, Klintsy J, Reyes-Terán, Gustavo, Sotelo, Julio, Jung-Cook, Helgi, Aguirre-Cruz, Lucinda
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364635/ https://www.ncbi.nlm.nih.gov/pubmed/25788967 http://dx.doi.org/10.1186/s12981-015-0048-9

Ejemplares similares

Electronic Structure of the Azide Group in 3′-Azido-3′-deoxythymidine (AZT) Compared to Small Azide Compounds
por: Chen, Fang-Fang, et al.
Publicado: (2009)

Inhibition of NF-κB activation sensitizes U937 cells to 3′-azido-3′-deoxythymidine induced apoptosis
por: Matteucci, C, et al.
Publicado: (2010)

Effect of 3`-Azido-3`-Deoxythymidine (AZT) on Telomerase Activity and Proliferation of HO-8910 Cell Line of Ovarian Cancer
por: Dinman, Jonathan D.
Publicado: (2006)

Effect of 3`-Azido-3`-Deoxythymidine (AZT) on Telomerase Activity and Proliferation of HO-8910 Cell Line of Ovarian Cancer
por: Li, Hongmei, et al.
Publicado: (2006)

Experimental Studies on Potentiation of the Antitumor Activity of 5‐Fluorouracil with 3′‐Azido‐3‐deoxythymidine for the Gastric Cancer Cell Line MKN28 in vivo
por: Yasuda, Chikao, et al.
Publicado: (1997)

Crystal structure of ammonium 3′-azido-3′-deoxythymidine-5′-aminocarbonylphosphonate hemihydrate: an anti-HIV agent
por: Jasko, Maxim V., et al.
Publicado: (2014)

Stabilization of Active Site Dynamics Leads to Increased Activity with 3′-Azido-3′-deoxythymidine Monophosphate for F105Y Mutant Human Thymidylate Kinase
por: Fucci, Ian J., et al.
Publicado: (2020)

Sildenafil Inhibits Myelin Expression and Myelination of Oligodendroglial Precursor Cells
por: Muñoz-Esquivel, Jonathan, et al.
Publicado: (2019)

Phenyl 1,2,3-Triazole-Thymidine Ligands Stabilize G-Quadruplex DNA, Inhibit DNA Synthesis and Potentially Reduce Tumor Cell Proliferation over 3′-Azido Deoxythymidine
por: Mahesh Kumar, Jerald, et al.
Publicado: (2013)

Connection Domain Mutations N348I and A360V in HIV-1 Reverse Transcriptase Enhance Resistance to 3′-Azido-3′-deoxythymidine through Both RNase H-dependent and -independent Mechanisms
por: Ehteshami, Maryam, et al.
Publicado: (2008)

APOBEC3G mRNA expression in exposed seronegative and early stage HIV infected individuals decreases with removal of exposure and with disease progression
por: Vázquez-Pérez, Joel A, et al.
Publicado: (2009)

Parenteral Quinacrine in Malarial Fevers
por: Basumullick, K. L., et al.
Publicado: (1947)

Treatment of Oriental Sore with Quinacrine
por: Sachdeva, Y. V.
Publicado: (1943)

3α-Azido-5-cholestene
por: Houston, Todd A., et al.
Publicado: (2008)

2'-Deoxythymidine Adducts from the Anti-HIV Drug Nevirapine
por: Antunes, Alexandra M. M., et al.
Publicado: (2013)

Quinacrine, an Antimalarial Drug with Strong Activity Inhibiting SARS-CoV-2 Viral Replication In Vitro
por: Salas Rojas, Mónica, et al.
Publicado: (2021)

Pharmacokinetics of quinacrine in the treatment of prion disease
por: Yung, Lotus, et al.
Publicado: (2004)

Toxic Symptoms Associated with Quinacrine Treatment
por: Nandi, D. K.
Publicado: (1947)

Quinacrine in the Eradication of Giardia Lamblia Infection
por: Pant, K. C., et al.
Publicado: (1942)

Quinacrine Treatment of Nitroimidazole-Refractory Giardiasis
por: Ydsten, Karin A, et al.
Publicado: (2021)

Deoxythymidine kinase in the tumour cells and serum of patients with non-Hodgkin lymphomas.
por: Rehn, S., et al.
Publicado: (1995)

Increased deoxythymidine triphosphate levels is a feature of relative cognitive decline
por: Desler, Claus, et al.
Publicado: (2015)

RADIOAUTOGRAPHIC LOCALIZATION OF DEOXYTHYMIDINE TRIPHOSPHATE IN TRADESCANTIA POLLEN GRAINS DURING DNA SYNTHESIS
por: Takats, S. T.
Publicado: (1968)

A four-year surveillance program for detection of Plasmodium falciparum chloroquine resistance in Honduras
por: Fontecha, Gustavo A, et al.
Publicado: (2014)

Design, Synthesis, and In Vitro and In Vivo Biological Studies of a 3′-Deoxythymidine Conjugate that Potentially Kills Cancer Cells Selectively
por: Wei, Qiong, et al.
Publicado: (2012)

A new family of globally distributed lytic roseophages with unusual deoxythymidine to deoxyuridine substitution
por: Rihtman, Branko, et al.
Publicado: (2021)

Candidate drug replacements for quinacrine in cutaneous lupus erythematosus
por: Yan, Daisy, et al.
Publicado: (2020)

Transporter Inhibition Profile for the Antivirals Tilorone, Quinacrine and Pyronaridine
por: Vignaux, Patricia A., et al.
Publicado: (2023)

Diastereoselective Synthesis of 2-Phenylselenenyl-1,3-anti-Diols and 2-Phenylselenenyl-1,3-anti-Azido-Alcohols via Hydroxy- and Azido-Selenenylation Reactions
por: Riela, Serena, et al.
Publicado: (2005)

The use of serum deoxythymidine kinase as a prognostic marker, and in the monitoring of patients with non-Hodgkin's lymphoma.
por: Gronowitz, J. S., et al.
Publicado: (1983)

Structural insights into RNA polymerase III-mediated transcription termination through trapping poly-deoxythymidine
por: Hou, Haifeng, et al.
Publicado: (2021)

Continuous Quinacrine Treatment Results in the Formation of Drug-Resistant Prions
por: Ghaemmaghami, Sina, et al.
Publicado: (2009)

Repurposing Pyramax®, quinacrine and tilorone as treatments for Ebola virus disease
por: Lane, Thomas R., et al.
Publicado: (2020)

Quinacrine, an Old Drug with Potentially usefull in the Treatment for COVID-19
por: PINEDA, BENJAMIN
Publicado: (2021)

Multimodal Investigation into the Interaction of Quinacrine with Microcavity-Supported Lipid Bilayers
por: Sarangi, Nirod Kumar, et al.
Publicado: (2022)

Dicyclohexylammonium (S)-2-azido-3-phenylpropanoate
por: Petrik, Sebastian J., et al.
Publicado: (2012)

Phosphine and carbene azido-cations: [(L)N(3)](+) and [(L)(2)N(3)](+)
por: Winkelhaus, Daniel, et al.
Publicado: (2015)

Chloroquine commonly induces hormetic dose responses
por: Calabrese, Edward J., et al.
Publicado: (2021)

The Repurposed Drugs Suramin and Quinacrine Cooperatively Inhibit SARS-CoV-2 3CL(pro) In Vitro
por: Eberle, Raphael J., et al.
Publicado: (2021)

Endometrial abnormalities on transvaginal ultrasonography and histopathology in women after quinacrine sterilization
por: Afzal, Saira, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_0ts9t91b6mkm1i9n8uevmmeje7