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Deregulation of microRNAs Let-7a and miR-21 mediate aberrant STAT3 signaling during human papillomavirus-induced cervical carcinogenesis: role of E6 oncoprotein

BACKGROUND: Aberrantly expressed and constitutively active STAT3 signaling plays a pivotal role in initiation and progression of human papillomavirus-induced cervical carcinogenesis. However, the underlying mechanism(s) responsible for pleiotropic effects of STAT3 signaling is poorly understood. In...

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Detalles Bibliográficos
Autores principales: Shishodia, Gauri, Verma, Gaurav, Srivastava, Yogesh, Mehrotra, Ravi, Das, Bhudev Chandra, Bharti, Alok Chandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364636/
https://www.ncbi.nlm.nih.gov/pubmed/25539644
http://dx.doi.org/10.1186/1471-2407-14-996