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Inhibition of GPR30 by estriol prevents growth stimulation of triple-negative breast cancer cells by 17β-estradiol

BACKGROUND: Due to the lack of ERα, triple negative breast cancers (TNBCs) are not susceptible to endocrine therapy using antiestrogens. However, the majority of TNBCs express the membrane bound estrogen receptor GPR30. We have recently shown that knock-down of GPR30 expression prevented growth stim...

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Detalles Bibliográficos
Autores principales: Girgert, Rainer, Emons, Günter, Gründker, Carsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364648/
https://www.ncbi.nlm.nih.gov/pubmed/25496649
http://dx.doi.org/10.1186/1471-2407-14-935