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Mediation of exogenous hydrogen sulfide in recovery of ischemic post-conditioning-induced cardioprotection via down-regulating oxidative stress and up-regulating PI3K/Akt/GSK-3β pathway in isolated aging rat hearts

The physiological and pathological roles of hydrogen sulfide (H(2)S) in the regulation of cardiovascular functions have been recognized. Cystathionine gamma-lyase (CSE) is a major H(2)S-producing enzyme in cardiovascular system. Ischemic post-conditioning (PC) provides cadioprotection in young heart...

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Detalles Bibliográficos
Autores principales: Li, Hongzhu, Wang, Yuehong, Wei, Can, Bai, Shuzhi, Zhao, Yajun, Li, Hongxia, Wu, Bo, Wang, Rui, Wu, Lingyun, Xu, Changqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364662/
https://www.ncbi.nlm.nih.gov/pubmed/25789157
http://dx.doi.org/10.1186/s13578-015-0003-4