Male-Biased Aganglionic Megacolon in the TashT Mouse Line Due to Perturbation of Silencer Elements in a Large Gene Desert of Chromosome 10

Neural crest cells (NCC) are a transient migratory cell population that generates diverse cell types such as neurons and glia of the enteric nervous system (ENS). Via an insertional mutation screen for loci affecting NCC development in mice, we identified one line—named TashT—that displays a partial...

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Detalles Bibliográficos
Autores principales: Bergeron, Karl-F., Cardinal, Tatiana, Touré, Aboubacrine M., Béland, Mélanie, Raiwet, Diana L., Silversides, David W., Pilon, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364714/
https://www.ncbi.nlm.nih.gov/pubmed/25786024
http://dx.doi.org/10.1371/journal.pgen.1005093

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364714/
https://www.ncbi.nlm.nih.gov/pubmed/25786024
http://dx.doi.org/10.1371/journal.pgen.1005093

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