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The Non-Benzodiazepine Anxiolytic Drug Etifoxine Causes a Rapid, Receptor-Independent Stimulation of Neurosteroid Biosynthesis

Neurosteroids can modulate the activity of the GABA(A) receptors, and thus affect anxiety-like behaviors. The non-benzodiazepine anxiolytic compound etifoxine has been shown to increase neurosteroid concentrations in brain tissue but the mode of action of etifoxine on neurosteroid formation has not...

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Detalles Bibliográficos
Autores principales: do Rego, Jean Luc, Vaudry, David, Vaudry, Hubert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364751/
https://www.ncbi.nlm.nih.gov/pubmed/25785994
http://dx.doi.org/10.1371/journal.pone.0120473