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Comparative Efficacy of (177)Lu and (90)Y for Anti-CD20 Pretargeted Radioimmunotherapy in Murine Lymphoma Xenograft Models

PURPOSE: Pretargeted radioimmunotherapy (PRIT) is a multi-step method of selectively delivering high doses of radiotherapy to tumor cells while minimizing exposure to surrounding tissues. Yttrium-90 ((90)Y) and lutetium-177 ((177)Lu) are two of the most promising beta-particle emitting radionuclides...

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Detalles Bibliográficos
Autores principales: Frost, Sofia H. L., Frayo, Shani L., Miller, Brian W., Orozco, Johnnie J., Booth, Garrett C., Hylarides, Mark D., Lin, Yukang, Green, Damian J., Gopal, Ajay K., Pagel, John M., Bäck, Tom A., Fisher, Darrell R., Press, Oliver W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364776/
https://www.ncbi.nlm.nih.gov/pubmed/25785845
http://dx.doi.org/10.1371/journal.pone.0120561