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MicroRNA-125b modulates inflammatory chemokine CCL4 expression in immune cells and its reduction causes CCL4 increase with age

Chemokines play a pivotal role in regulating the immune response through a tightly controlled expression. Elevated levels of inflammatory chemokines commonly occur with aging but the mechanism underlying this age-associated change is not fully understood. Here, we report the role of microRNA-125b (m...

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Detalles Bibliográficos
Autores principales: Cheng, Nai-Lin, Chen, Xiaochun, Kim, Jiewan, Shi, Alvin H, Nguyen, Cuong, Wersto, Robert, Weng, Nan-ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364832/
https://www.ncbi.nlm.nih.gov/pubmed/25620312
http://dx.doi.org/10.1111/acel.12294