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Aberrant post-translational modifications compromise human myosin motor function in old age

Novel experimental methods, including a modified single fiber in vitro motility assay, X-ray diffraction experiments, and mass spectrometry analyses, have been performed to unravel the molecular events underlying the aging-related impairment in human skeletal muscle function at the motor protein lev...

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Detalles Bibliográficos
Autores principales: Li, Meishan, Ogilvie, Hannah, Ochala, Julien, Artemenko, Konstantin, Iwamoto, Hiroyuki, Yagi, Naoto, Bergquist, Jonas, Larsson, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364835/
https://www.ncbi.nlm.nih.gov/pubmed/25645586
http://dx.doi.org/10.1111/acel.12307