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Aberrant post-translational modifications compromise human myosin motor function in old age
Novel experimental methods, including a modified single fiber in vitro motility assay, X-ray diffraction experiments, and mass spectrometry analyses, have been performed to unravel the molecular events underlying the aging-related impairment in human skeletal muscle function at the motor protein lev...
Autores principales: | Li, Meishan, Ogilvie, Hannah, Ochala, Julien, Artemenko, Konstantin, Iwamoto, Hiroyuki, Yagi, Naoto, Bergquist, Jonas, Larsson, Lars |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364835/ https://www.ncbi.nlm.nih.gov/pubmed/25645586 http://dx.doi.org/10.1111/acel.12307 |
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