Comparative analysis of genome maintenance genes in naked mole rat, mouse, and human

Genome maintenance (GM) is an essential defense system against aging and cancer, as both are characterized by increased genome instability. Here, we compared the copy number variation and mutation rate of 518 GM-associated genes in the naked mole rat (NMR), mouse, and human genomes. GM genes appeare...

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Detalles Bibliográficos
Autores principales: MacRae, Sheila L, Zhang, Quanwei, Lemetre, Christophe, Seim, Inge, Calder, Robert B, Hoeijmakers, Jan, Suh, Yousin, Gladyshev, Vadim N, Seluanov, Andrei, Gorbunova, Vera, Vijg, Jan, Zhang, Zhengdong D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Short Takes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364841/
https://www.ncbi.nlm.nih.gov/pubmed/25645816
http://dx.doi.org/10.1111/acel.12314

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364841/
https://www.ncbi.nlm.nih.gov/pubmed/25645816
http://dx.doi.org/10.1111/acel.12314

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