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Single muscle fiber proteomics reveals unexpected mitochondrial specialization

Mammalian skeletal muscles are composed of multinucleated cells termed slow or fast fibers according to their contractile and metabolic properties. Here, we developed a high-sensitivity workflow to characterize the proteome of single fibers. Analysis of segments of the same fiber by traditional and...

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Detalles Bibliográficos
Autores principales: Murgia, Marta, Nagaraj, Nagarjuna, Deshmukh, Atul S, Zeiler, Marlis, Cancellara, Pasqua, Moretti, Irene, Reggiani, Carlo, Schiaffino, Stefano, Mann, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364878/
https://www.ncbi.nlm.nih.gov/pubmed/25643707
http://dx.doi.org/10.15252/embr.201439757