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Single muscle fiber proteomics reveals unexpected mitochondrial specialization
Mammalian skeletal muscles are composed of multinucleated cells termed slow or fast fibers according to their contractile and metabolic properties. Here, we developed a high-sensitivity workflow to characterize the proteome of single fibers. Analysis of segments of the same fiber by traditional and...
Autores principales: | Murgia, Marta, Nagaraj, Nagarjuna, Deshmukh, Atul S, Zeiler, Marlis, Cancellara, Pasqua, Moretti, Irene, Reggiani, Carlo, Schiaffino, Stefano, Mann, Matthias |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364878/ https://www.ncbi.nlm.nih.gov/pubmed/25643707 http://dx.doi.org/10.15252/embr.201439757 |
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