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Cell Cycle–Dependent Differentiation Dynamics Balances Growth and Endocrine Differentiation in the Pancreas

Organogenesis relies on the spatiotemporal balancing of differentiation and proliferation driven by an expanding pool of progenitor cells. In the mouse pancreas, lineage tracing at the population level has shown that the expanding pancreas progenitors can initially give rise to all endocrine, ductal...

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Detalles Bibliográficos
Autores principales: Kim, Yung Hae, Larsen, Hjalte List, Rué, Pau, Lemaire, Laurence A., Ferrer, Jorge, Grapin-Botton, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364879/
https://www.ncbi.nlm.nih.gov/pubmed/25786211
http://dx.doi.org/10.1371/journal.pbio.1002111