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Prioritizing Therapeutics for Lung Cancer: An Integrative Meta-analysis of Cancer Gene Signatures and Chemogenomic Data

Repurposing FDA-approved drugs with the aid of gene signatures of disease can accelerate the development of new therapeutics. A major challenge to developing reliable drug predictions is heterogeneity. Different gene signatures of the same disease or drug treatment often show poor overlap across stu...

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Detalles Bibliográficos
Autores principales: Fortney, Kristen, Griesman, Joshua, Kotlyar, Max, Pastrello, Chiara, Angeli, Marc, Sound-Tsao, Ming, Jurisica, Igor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364883/
https://www.ncbi.nlm.nih.gov/pubmed/25786242
http://dx.doi.org/10.1371/journal.pcbi.1004068