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Design and Evaluation of Optimized Artificial HIV-1 Poly-T Cell-Epitope Immunogens
A successful HIV vaccine in addition to induction of antibody responses should elicit effective T cell responses. Here we described possible strategies for rational design of T-cell vaccine capable to induce high levels of both CD4+ and CD8+ T- cell responses. We developed artificial HIV-1 polyepito...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364888/ https://www.ncbi.nlm.nih.gov/pubmed/25786238 http://dx.doi.org/10.1371/journal.pone.0116412 |