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Design and Evaluation of Optimized Artificial HIV-1 Poly-T Cell-Epitope Immunogens

A successful HIV vaccine in addition to induction of antibody responses should elicit effective T cell responses. Here we described possible strategies for rational design of T-cell vaccine capable to induce high levels of both CD4+ and CD8+ T- cell responses. We developed artificial HIV-1 polyepito...

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Detalles Bibliográficos
Autores principales:	Reguzova, Alena, Antonets, Denis, Karpenko, Larisa, Ilyichev, Alexander, Maksyutov, Rinat, Bazhan, Sergei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364888/ https://www.ncbi.nlm.nih.gov/pubmed/25786238 http://dx.doi.org/10.1371/journal.pone.0116412

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