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Ruta graveolens L. Induces Death of Glioblastoma Cells and Neural Progenitors, but Not of Neurons, via ERK 1/2 and AKT Activation

Glioblastoma multiforme is a highly aggressive brain tumor whose prognosis is very poor. Due to early invasion of brain parenchyma, its complete surgical removal is nearly impossible, and even after aggressive combined treatment (association of surgery and chemo- and radio-therapy) five-year surviva...

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Detalles Bibliográficos
Autores principales: Gentile, Maria Teresa, Ciniglia, Claudia, Reccia, Mafalda G., Volpicelli, Floriana, Gatti, Monica, Thellung, Stefano, Florio, Tullio, Melone, Mariarosa A. B., Colucci-D’Amato, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364962/
https://www.ncbi.nlm.nih.gov/pubmed/25785932
http://dx.doi.org/10.1371/journal.pone.0118864