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Ruta graveolens L. Induces Death of Glioblastoma Cells and Neural Progenitors, but Not of Neurons, via ERK 1/2 and AKT Activation
Glioblastoma multiforme is a highly aggressive brain tumor whose prognosis is very poor. Due to early invasion of brain parenchyma, its complete surgical removal is nearly impossible, and even after aggressive combined treatment (association of surgery and chemo- and radio-therapy) five-year surviva...
Autores principales: | Gentile, Maria Teresa, Ciniglia, Claudia, Reccia, Mafalda G., Volpicelli, Floriana, Gatti, Monica, Thellung, Stefano, Florio, Tullio, Melone, Mariarosa A. B., Colucci-D’Amato, Luca |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364962/ https://www.ncbi.nlm.nih.gov/pubmed/25785932 http://dx.doi.org/10.1371/journal.pone.0118864 |
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