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Lens Status Influences the Association between CFH Polymorphisms and Age-Related Macular Degeneration: Findings from Two Population-Based Studies in Singapore

AIMS: To determine the differential effects of genetic polymorphism in CFH and ARMS2 on risk of age-related macular degeneration (AMD) between phakic vs. pseudophakic/aphakic eyes. METHODS: 9,529 eyes of 4,918 participants from the Singapore Malay Eye Study and Singapore Indian Eye Study were analyz...

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Detalles Bibliográficos
Autores principales: Wong, Chee Wai, Liao, Jiemin, Cheung, Gemmy C., Khor, Chiea Chuen, Vithana, Eranga N., Wang, Jie Jin, Mitchell, Paul, Aung, Tin, Wong, Tien Y., Cheng, Ching-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364964/
https://www.ncbi.nlm.nih.gov/pubmed/25786237
http://dx.doi.org/10.1371/journal.pone.0119570