Detection of EML4-ALK in Lung Adenocarcinoma Using Pleural Effusion with FISH, IHC, and RT-PCR Methods

Anaplastic lymphoma kinase (ALK) and echinoderm microtubule-associated protein-like 4 (EML4) gene rearrangements occur in approximately 5% of non-small-cell lung cancers (NSCLC), leading to the overexpression of anaplastic lymphoma kinase and predicting a response to the targeted inhibitor, crizotin...

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Detalles Bibliográficos
Autores principales: Liu, Leilei, Zhan, Ping, Zhou, Xiaodie, Song, Yong, Zhou, Xiaojun, Yu, Like, Wang, Jiandong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364974/
https://www.ncbi.nlm.nih.gov/pubmed/25785456
http://dx.doi.org/10.1371/journal.pone.0117032

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364974/
https://www.ncbi.nlm.nih.gov/pubmed/25785456
http://dx.doi.org/10.1371/journal.pone.0117032

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