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Short-Term Treatment with Diminazene Aceturate Ameliorates the Reduction in Kidney ACE2 Activity in Rats with Subtotal Nephrectomy

Angiotensin converting enzyme (ACE) 2 is an important modulator of the renin angiotensin system (RAS) through its role to degrade angiotensin (Ang) II. Depletion of kidney ACE2 occurs following kidney injury due to renal mass reduction and may contribute to progressive kidney disease. This study ass...

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Detalles Bibliográficos
Autores principales: Velkoska, Elena, Patel, Sheila K., Griggs, Karen, Pickering, Raelene J., Tikellis, Chris, Burrell, Louise M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364975/
https://www.ncbi.nlm.nih.gov/pubmed/25786223
http://dx.doi.org/10.1371/journal.pone.0118758