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Within-Host Stochastic Emergence Dynamics of Immune-Escape Mutants
Predicting the emergence of new pathogenic strains is a key goal of evolutionary epidemiology. However, the majority of existing studies have focussed on emergence at the population level, and not within a host. In particular, the coexistence of pre-existing and mutated strains triggers a heightened...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365036/ https://www.ncbi.nlm.nih.gov/pubmed/25785434 http://dx.doi.org/10.1371/journal.pcbi.1004149 |