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Methotrexate as combination partner of TNF inhibitors and tocilizumab. What is reasonable from an immunological viewpoint?
The goal of therapy of rheumatoid arthritis is to achieve a remission or at least low disease activity. TNF inhibitors induce high remission rates only in combination with methotrexate, whereas the efficacy of tocilizumab is optimal even as a monotherapy. In this article, the differing dependence of...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer London
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365184/ https://www.ncbi.nlm.nih.gov/pubmed/25604317 http://dx.doi.org/10.1007/s10067-015-2861-x |