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A pathway from chromosome transfer to engineering resulting in human and mouse artificial chromosomes for a variety of applications to bio-medical challenges

Microcell-mediated chromosome transfer (MMCT) is a technique to transfer a chromosome from defined donor cells into recipient cells and to manipulate chromosomes as gene delivery vectors and open a new avenue in somatic cell genetics. However, it is difficult to uncover the function of a single spec...

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Detalles Bibliográficos
Autores principales: Oshimura, Mitsuo, Uno, Narumi, Kazuki, Yasuhiro, Katoh, Motonobu, Inoue, Toshiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365188/
https://www.ncbi.nlm.nih.gov/pubmed/25657031
http://dx.doi.org/10.1007/s10577-014-9459-z