Developing de novo human artificial chromosomes in embryonic stem cells using HSV-1 amplicon technology

De novo artificial chromosomes expressing genes have been generated in human embryonic stem cells (hESc) and are maintained following differentiation into other cell types. Human artificial chromosomes (HAC) are small, functional, extrachromosomal elements, which behave as normal chromosomes in huma...

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Detalles Bibliográficos
Autores principales: Moralli, Daniela, Monaco, Zoia L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365269/
https://www.ncbi.nlm.nih.gov/pubmed/25657030
http://dx.doi.org/10.1007/s10577-014-9456-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365269/
https://www.ncbi.nlm.nih.gov/pubmed/25657030
http://dx.doi.org/10.1007/s10577-014-9456-2

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