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Developing de novo human artificial chromosomes in embryonic stem cells using HSV-1 amplicon technology
De novo artificial chromosomes expressing genes have been generated in human embryonic stem cells (hESc) and are maintained following differentiation into other cell types. Human artificial chromosomes (HAC) are small, functional, extrachromosomal elements, which behave as normal chromosomes in huma...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer Netherlands
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365269/ https://www.ncbi.nlm.nih.gov/pubmed/25657030 http://dx.doi.org/10.1007/s10577-014-9456-2 |