Inhibition of Osteoclast Activation by Phloretin through Disturbing αvβ3 Integrin-c-Src Pathway

This study was to explore the sequential signaling of disorganization of the actin cytoskeletal architecture by phloretin. RAW 264.7 macrophages were incubated with 1–20 μM phloretin for 5 days in the presence of RANKL. C57BL/6 mice were ovariectomized (OVX) and orally treated with 10 mg/kg phloreti...

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Detalles Bibliográficos
Autores principales: Lee, Eun-Jung, Kim, Jung-Lye, Gong, Ju-Hyun, Park, Sin-Hye, Kang, Young-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365379/
https://www.ncbi.nlm.nih.gov/pubmed/25834823
http://dx.doi.org/10.1155/2015/680145

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365379/
https://www.ncbi.nlm.nih.gov/pubmed/25834823
http://dx.doi.org/10.1155/2015/680145

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