ICAM-5 affects spine maturation by regulation of NMDA receptor binding to α-actinin

ICAM-5 is a negative regulator of dendritic spine maturation and facilitates the formation of filopodia. Its absence results in improved memory functions, but the mechanisms have remained poorly understood. Activation of NMDA receptors induces ICAM-5 ectodomain cleavage through a matrix metalloprote...

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Detalles Bibliográficos
Autores principales: Ning, Lin, Paetau, Sonja, Nyman-Huttunen, Henrietta, Tian, Li, Gahmberg, Carl G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365481/
https://www.ncbi.nlm.nih.gov/pubmed/25572420
http://dx.doi.org/10.1242/bio.201410439

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365481/
https://www.ncbi.nlm.nih.gov/pubmed/25572420
http://dx.doi.org/10.1242/bio.201410439

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