Tyrosine motifs are required for prestin basolateral membrane targeting

Prestin is targeted to the lateral wall of outer hair cells (OHCs) where its electromotility is critical for cochlear amplification. Using MDCK cells as a model system for polarized epithelial sorting, we demonstrate that prestin uses tyrosine residues, in a YXXΦ motif, to target the basolateral sur...

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Detalles Bibliográficos
Autores principales: Zhang, Yifan, Moeini-Naghani, Iman, Bai, JunPing, Santos-Sacchi, Joseph, Navaratnam, Dhasakumar S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365488/
https://www.ncbi.nlm.nih.gov/pubmed/25596279
http://dx.doi.org/10.1242/bio.201410629

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365488/
https://www.ncbi.nlm.nih.gov/pubmed/25596279
http://dx.doi.org/10.1242/bio.201410629

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