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mir-34b/c and mir-449a/b/c are required for spermatogenesis, but not for the first cleavage division in mice
Mammalian sperm are carriers of not only the paternal genome, but also the paternal epigenome in the forms of DNA methylation, retained histones and noncoding RNAs. Although paternal DNA methylation and histone retention sites have been correlated with protein-coding genes that are critical for prei...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Company of Biologists
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365490/ https://www.ncbi.nlm.nih.gov/pubmed/25617420 http://dx.doi.org/10.1242/bio.201410959 |