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Netrins and Frazzled/DCC promote the migration and mesenchymal to epithelial transition of Drosophila midgut cells

Mesenchymal-epithelial transitions (METs) are important in both development and the growth of secondary tumours. Although the molecular basis for epithelial polarity is well studied, less is known about the cues that induce MET. Here we show that Netrins, well known as chemotropic guidance factors,...

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Detalles Bibliográficos
Autores principales: Pert, Melissa, Gan, Miao, Saint, Robert, Murray, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365492/
https://www.ncbi.nlm.nih.gov/pubmed/25617422
http://dx.doi.org/10.1242/bio.201410827