Cargando…
Netrins and Frazzled/DCC promote the migration and mesenchymal to epithelial transition of Drosophila midgut cells
Mesenchymal-epithelial transitions (METs) are important in both development and the growth of secondary tumours. Although the molecular basis for epithelial polarity is well studied, less is known about the cues that induce MET. Here we show that Netrins, well known as chemotropic guidance factors,...
Autores principales: | Pert, Melissa, Gan, Miao, Saint, Robert, Murray, Michael J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365492/ https://www.ncbi.nlm.nih.gov/pubmed/25617422 http://dx.doi.org/10.1242/bio.201410827 |
Ejemplares similares
-
The Drosophila Netrin receptor frazzled/DCC functions as an invasive tumor suppressor
por: VanZomeren-Dohm, Adrienne, et al.
Publicado: (2011) -
Frazzled promotes growth cone attachment at the source of a Netrin gradient in the Drosophila visual system
por: Akin, Orkun, et al.
Publicado: (2016) -
Netrin1/DCC signaling promotes neuronal migration in the dorsal spinal cord
por: Junge, Harald J., et al.
Publicado: (2016) -
Netrin-1 – DCC Signaling Systems and Age-Related Macular Degeneration
por: SanGiovanni, John Paul, et al.
Publicado: (2015) -
Frazzled can act through distinct molecular pathways in epithelial cells to regulate motility, apical constriction, and localisation of E-Cadherin
por: Golenkina, Sofia, et al.
Publicado: (2018)