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Increased DNA methylation of the SLC30A8 gene promoter is associated with type 2 diabetes in a Malay population

BACKGROUND: Recent studies have demonstrated that DNA polymorphisms in the solute carrier family 30 member 8 (SLC30A8) gene confer the risk susceptibility to type 2 diabetes (T2D). The present study aimed to analyze DNA methylation levels of this gene in T2D and diabetic nephropathy (DN). RESULTS: W...

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Detalles Bibliográficos
Autores principales: Seman, Norhashimah Abu, Mohamud, Wan Nazaimoon Wan, Östenson, Claes-Göran, Brismar, Kerstin, Gu, Harvest F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365519/
https://www.ncbi.nlm.nih.gov/pubmed/25793017
http://dx.doi.org/10.1186/s13148-015-0049-5