Pancancer analysis of DNA methylation-driven genes using MethylMix

Aberrant DNA methylation is an important mechanism that contributes to oncogenesis. Yet, few algorithms exist that exploit this vast dataset to identify hypo- and hypermethylated genes in cancer. We developed a novel computational algorithm called MethylMix to identify differentially methylated gene...

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Detalles Bibliográficos
Autores principales: Gevaert, Olivier, Tibshirani, Robert, Plevritis, Sylvia K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365533/
https://www.ncbi.nlm.nih.gov/pubmed/25631659
http://dx.doi.org/10.1186/s13059-014-0579-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365533/
https://www.ncbi.nlm.nih.gov/pubmed/25631659
http://dx.doi.org/10.1186/s13059-014-0579-8

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